Citrulline is a non-essential amino acid that is that is found in melons. It is an important intermediate in the urea cycle, functioning along with Arginine and Ornithine to rid the body of ammonia, a byproduct of protein metabolism. Because Citrulline is a precursor of Arginine, it provides a readily available source material for Arginine production, which in turn, can be used for the production of Nitric Oxide (NO). NO plays a fundamental role in vascular function and blood flow. Citrulline therefore, not only supports detoxification pathways, but also supports NO production and a healthy cardiovascular system. Nitric Oxide (NO) deficiency contributes to nearly every major disease of our time-cardiovascular disease, heart attack, stroke, cancer, hardening of the arteries, high blood pressure, arthritis, complications of diabetes, ulcers and Alzheimer and erectile dysfunction. It is a natural remedy for men and women of all ages, refreshing and rejuvenated substance.